Notice - Notification of WTO Members: Commission Regulation (EU) 2019/799 amending Annex I to Regulation (EC) No 1334/2008 of the European Parliament and of the Council as regards removal from the Union list of the flavouring substance furan- 2(5H)-one (FLno 10.066)


WTO code G/SPS/N/EU/325
Date notice 05/06/2019
Notice type Regular
Title Commission Regulation (EU) 2019/799 amending Annex I to Regulation (EC) No 1334/2008 of the European Parliament and of the Council as regards removal from the Union list of the flavouring substance furan- 2(5H)-one (FLno 10.066)
Summary

The Union list of flavourings and source materials is laid down in  Annex  I  to  Regulation  (EC)  No  1334/3008.  It  was  established  by  Commission Implementing  Regulation  (EU)  No  872/2012  of  1  October  2012  adopting  the  list  of flavouring substances notified in G/SPS/N/EU/13/Add.1 (12 October 2012) which is now amended by this Regulation.
This addendum concerns the removal of the flavouring substance furan-2(5H)-one (FLno 10.066) from the European Union list of flavourings following the European Food Safety 
Authority  opinion  published  at  the  end  of  January  2019  which  concluded  that  this substance  is  genotoxic  in vivo  and  therefore  its  use  as  a  flavouring  substance  raises  a safety concern.
The  measure  has  been  taken  in  urgency  in  view  of  this  EFSA  assessment  indicating  a serious  risk  (genotoxicity)  of  this  flavouring  substance  FL  10.066  on  the  basis  of  new scientific data. Therefore, its addition to foods should be stopped swiftly. It has not been possible to notify the draft measure in view of the nature of the risk involved.
According to the European Association of producers of flavourings (EFFA) as reported in the opinion by EFSA, the poundage for this substance in Europe is very low (zero in 2017).
This substance furan-2(5H)-one (FL No 10.066) can also be identified with CAS No. 497-23-4, JECFA No 2000 and JECFA name "4-hydroxy-2-butenoic acid gamma lactone".
The EFSA opinion is available as EFSA Scientific Opinion on Flavouring Group Evaluation 217  Revision  2  (FGE.217Rev2),  consideration  of  genotoxicity  potential  for  alpha,  beta

Product Flavourings, food
Country European Union

File attach:
NEU325.pdf

Orther Notice:


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G/SPS/N/USA/3537 - Green Innovation GmbH; Filing of Food Additive Petition (Animal Use); Notification of Petition.
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G/SPS/N/TUR/15/Add.1 - Approved Establishment System of the Republic of Türkiye for the Importation of Certain Animal-Origin Foods
G/SPS/N/COL/368/Add.1 - Resolución No. 00030058 del 25 de noviembre de 2025 del Instituto Colombiano Agropecuario - ICA "Por la cual se establece el Programa de Inspección en Puntos de Origen Habilitados para las Exportaciones por Vía Marítima de Flor Cortada, Follaje y Fruta Fresca desde el Territorio Colombiano"
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G/SPS/N/CAN/1592 - Proposal to modify the use of caffeine as a supplemental ingredient.
G/SPS/N/URY/103 - Proyecto de Resolución de la Dirección General de Servicios Ganaderos del Ministerio de Ganadería, Agricultura y Pesca por la que se aprueban los siguientes procedimientos: "Procedimiento para la Habilitación de Establecimientos de Cuarentenas y Unidades autorizadas para el alojamiento de équidos importados, Versión 1" y "Procedimiento para la Importación de Équidos, Versión 1".
G/SPS/N/CAN/1613/Add.1 - Proposed amendments to the Susceptible Species of Aquatic Animals List
G/SPS/N/EU/781 - Draft Commission Regulation (EU) amending Regulation (EU) No 142/2011 as regards requirements for the import of used cooking oil (Text with EEA relevance).
G/SPS/N/EU/781 - Draft Commission Regulation (EU) amending Regulation (EU) No 142/2011 as regards requirements for the import of used cooking oil (Text with EEA relevance).
G/SPS/N/AUS/502/Add.24 - Notification of emergency measures for Khapra beetle
G/SPS/N/KGZ/41 - Draft Decision of the Council of the Eurasian Economic Commission on Amendments to the Common Quarantine Phytosanitary Requirements for Regulated Products and Pests at the Customs Border and in the Customs Territory of the EAEU.
G/SPS/N/JPN/1375/Add.1 - Proposed revision of Ministerial Ordinance on the Specifications and Standards of Feeds and Feed Additives
G/SPS/N/AUS/502/Add.24/Corr.1 - Notification of emergency measures for Khapra beetle: Release of the draft pest risk analysis for khapra beetle (Trogoderma granarium) – Part 1
G/SPS/N/UKR/255 - Resolution of the Cabinet of Ministers of Ukraine No. 1478 "On Amendments to Certain Resolutions of the Cabinet of Ministers of Ukraine Concerning the Establishment and Maintenance of Registers, Implementation of Customs Control and Official Control Measures" of 19 November 2025.
G/SPS/N/UKR/254/Add.1 - Draft Order of the Ministry of Health of Ukraine "On approval of the procedure and methodology for assessing the impact on human health of vitamins, minerals and other substances and their maximum permissible doses in food products offered for circulation as dietary supplements"
G/SPS/N/KGZ/40 - Draft Decision of the Council of the Eurasian Economic Commission on Amendment to the List of Regulated Products (Consignments, Materials, Goods) Subject to Quarantine Phytosanitary Control (Surveillance) at the Customs Border of the Eurasian Economic Union and in the Customs Territory of the Eurasian Economic Union.
G/SPS/N/AUS/625 - Guidelines for the evaluation of overseas pre-export testing programs exporting uncooked prawns to Australia.
G/SPS/N/TPKM/650/Add.1 - Standards for Pesticide Residue Limits in Foods and Standards for Pesticide Residue Limits in Animal Products
G/SPS/N/URY/102 - Proyecto de Resolución de Prohibición de Solventes en base a tipos de hidrocarburos/cortes de petróleo y otras sustancias para la formulación de Productos Fitosanitarios.
G/SPS/N/URY/101 - Proyecto de Resolución de la Dirección General de Servicios Agrícolas por la que se aplican Restricciones de Uso al Clorpirifos. Idioma(s): español.
G/SPS/N/EU/898 - Draft Commission Implementing Regulation amending Regulation (EC) No 429/2008 as regards the application form for authorisations of feed additives and the designation of target animal species and categories (Text with EEA relevance).
G/SPS/N/HND/26 - Reglamento de Cuarentena Agropecuaria (Regulation on agricultural quarantine)
G/SPS/N/HND/11 - Reglamento para Embalaje de Madera Utilizado en el Comercio Internacional (Regulations on wood packaging material in international trade).
G/SPS/N/HND/17/Add.1 - Reglamento para la Producción, Procesamiento, Comercialización, Registro y Control de la Agricultura Orgánica
G/SPS/N/HND/16/Add.1 - Reglamento para el Registro, Uso y Control de Fertilizantes, Estimulantes, Enmiendas, Materias Primas y Sustancias Afines para uso Agrícola y Jardinería
G/SPS/N/HND/17 - Reglamento sobre Agricultura Orgánica (Regulation on organic agriculture)
G/SPS/N/HND/16 - Reglamento sobre el Registro, Uso y Control de Fertilizantes y Materias Primas (Regulation governing the registration, use and control of fertilizers and raw materials)
G/SPS/N/SLV/149 - Reglamento Técnico Salvadoreño RTS 55.02.01:25 Embalaje de madera. Medidas fitosanitarias, requisitos para el uso de la marca internacional y para el otorgamiento del registro.
G/SPS/N/EU/851/Add.2 - The listing and the measures for regulated non-quarantine pests
G/SPS/N/CAN/1625 - Proposal to modify the List of Permitted Food Enzymes to authorize the use of exo-inulinase.
G/SPS/N/TZA/487 - PCD 739: 2025, Dried raw seaweed - Specification, First Edition.
G/SPS/N/TUR/154 - Veterinary health certificate for products subject to veterinary controls for direct transit through Republic of Türkiye or for temporary storage intended for dispatch to another country/ship.
G/SPS/N/RUS/341 - Draft Decision of the Council of the Eurasian Economic Commission on Amendment to the List of Regulated Products (Consignments, Materials, Goods) Subject to Quarantine Phytosanitary Control (Surveillance) at the Customs Border of the Eurasian Economic Union and in the Customs Territory of the Eurasian Economic Union.
G/SPS/N/RUS/340 - Draft Decision of the Council of the Eurasian Economic Commission on Amendments to the Common Quarantine Phytosanitary Requirements for Regulated Products and Pests at the Customs Border and in the Customs Territory of the EAEU.
G/SPS/N/KOR/833 - Proposed revision of the "Enforcement Rule of the Special Act on Imported Food Safety Control".
G/SPS/N/EU/875/Add.1 - Transitional measures for plastic materials and articles manufactured with salicylic acid or untreated wood flour or fibres
G/SPS/N/CAN/1624 - Proposed Maximum Residue Limit: Spidoxamat (PMRL2025-27).
G/SPS/N/USA/3536 - Fluopyram; Pesticide Tolerances. Final rule.
G/SPS/N/USA/3535 - Fluazinam; Pesticide Tolerances. Final rule.
G/SPS/N/CAN/1623 - Proposed Maximum Residue Limit: Pyrethrins (PMRL2025-25).
G/SPS/N/CAN/1621 - RMD–25–03: Pest risk management document to deregulate Phytophthora abietivora in Canada.
G/SPS/N/CAN/1622 - Proposed Maximum Residue Limit: Penthiopyrad (PMRL2025-26).
G/SPS/N/BRA/2418/Add.1 - Draft Resolution 1337, 18 June 2025
G/SPS/N/BRA/2417/Add.1 - Draft Resolution 1335, 12 June 2025
G/SPS/N/BRA/2412/Add.1 - Draft Resolution 1333, 20 May 2025
G/SPS/N/BRA/2266/Add.1 - Draft Resolution number 1242, 20 March 2024
G/SPS/N/UGA/465 - DARS 1023:2025, Live grading for rabbits, guinea pigs and other small mammals — Specification.
G/SPS/N/UGA/464 - DARS 1851:2025, Animal husbandry guidelines for egg- laying flocks — Cage-free, First Edition.